| Name | Description | Rewards |
|---|---|---|
| The Den of Evil | Search Blood Moor for the Den of Evil. | 1 Skill Point; 1 Skills/Stats Reset (per difficulty) |
| Sisters' Burial Grounds | Search the Cold Plains for the path leading to the Burial Grounds. | 1 free mercenary hired; Ability to hire mercenaries |
| The Search for Cain | Search Dark Wood for the Tree of Inifuss, then the Cairn Stones. | A ring from Akara; Free item identification by Deckard Cain |
| The Forgotten Tower | Search the Stony Field for the tome; locate the tower in the Black Marsh. | One-time loot chest (per difficulty) |
| Tools of the Trade | Search the Barracks. Choose wisely which item you want to imbue. | Imbued item from Charsi |
| Sisters to the Slaughter | Find Catacombs Level 4 and kill Andariel. | Access to Act II; Quest drop: 2 Chipped Gems |
| Name | Description | Rewards |
|---|---|---|
| Radament's Lair | Search the Sewers below Lut Gholein. | Cost of buying items in Lut Gholein reduced by 10% |
| The Horadric Staff | Craft the Horadric Staff; find Tal Rasha's Burial Chamber. | Access to Tal Rasha's Chamber |
| The Tainted Sun | Search the Lost City for a clue to the whereabouts of the Claw Vipers. | Access to the Claw Viper Temple |
| The Arcane Sanctuary | Search the Palace for the Arcane Sanctuary. | Access to the Arcane Sanctuary |
| The Summoner | Find the Summoner in the Arcane Sanctuary. | Access to Canyon of the Magi |
| The Seven Tombs | Find the True Tomb of Tal Rasha. | Access to Act III |
| Name | Description | Rewards |
|---|---|---|
| The Golden Bird | Look for a Unique Monster in the Spider Forest. | Potion of Life |
| Blade of the Old Religion | Find the Pygmy Village in the Flayer Jungle. | A ring from Ormus; Free Iron Wolf if no mercenary yet |
| Khalim's Will | Forge Khalim's Will and destroy the Compelling Orb. | Access to the Durance of Hate |
| Lam Esen's Tome | The Tome is always in the Ruined Temple. | 5 Stat points; Cost of buying items in Kurast reduced by 10% |
| The Blackened Temple | Search Travincal for the Compelling Orb. | Access to the Durance of Hate |
| The Guardian | Search the Durance of Hate for Mephisto. | Access to Act IV |
| Name | Description | Rewards |
|---|---|---|
| The Hellforge | Search the River of Flame for the Hell Forge. | 1 random Rune; 1 Perfect Gem |
| The Fallen Angel | Search The Plains of Despair for Izual. | 2 Skill points |
| Terror's End | Enter the Chaos Sanctuary and break the Seals. | Access to Act V; New Title and next Difficulty (Classic) |
| Name | Description | Rewards |
|---|---|---|
| Siege on Harrogath | Search the Bloody Foothills for Shenk the Overseer. | Sockets an item once per difficulty; Harrogath items cost reduced by 50% |
| Rescue on Mount Arreat | Search the Frigid Highlands to rescue Barbarian captives. | Ability to hire Barbarian Mercenaries; Tal, Ral, and Ort |
| Betrayal of Harrogath | Find the Halls of Vaught to find Nihilathak the betrayer. | Anya will personalize an item |
| Prison of Ice | Find and search the Frozen River for Anya. | Scroll of Resistance; Rare class-specific item from Anya |
| Rite of Passage | Defeat the three Ancients on Arreat Summit. | Bonus to Experience |
| Eve of Destruction | Defeat Baal in the Worldstone Chamber. | New Title; Advance to next Difficulty (Expansion) |
| Pandemonium Event | Defeat the Uber Bosses | Hellfire Torch; Standard of Heroes |